t-viSNE: Interactive Assessment and Interpretation of t-SNE Projections
https://doi.org/10.1109/TVCG.2020.2986996
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14 KiB
14 KiB
1 | MouseID | DYRK1A_N | ITSN1_N | BDNF_N | NR1_N | NR2A_N | pAKT_N | pBRAF_N | pCAMKII_N | pCREB_N | pELK_N | pERK_N | pJNK_N | PKCA_N | pMEK_N | pNR1_N | pNR2A_N | pNR2B_N | pPKCAB_N | pRSK_N | AKT_N | BRAF_N | CAMKII_N | CREB_N | ELK_N | ERK_N | GSK3B_N | JNK_N | MEK_N | TRKA_N | RSK_N | APP_N | Bcatenin_N | SOD1_N | MTOR_N | P38_N | pMTOR_N | DSCR1_N | AMPKA_N | NR2B_N | pNUMB_N | RAPTOR_N | TIAM1_N | pP70S6_N | NUMB_N | P70S6_N | pGSK3B_N | pPKCG_N | CDK5_N | S6_N | ADARB1_N | AcetylH3K9_N | RRP1_N | BAX_N | ARC_N | ERBB4_N | nNOS_N | Tau_N | GFAP_N | GluR3_N | GluR4_N | IL1B_N | P3525_N | pCASP9_N | PSD95_N | SNCA_N | Ubiquitin_N | pGSK3B_Tyr216_N | SHH_N | BAD_N | BCL2_N | pS6_N | pCFOS_N | SYP_N | H3AcK18_N | EGR1_N | H3MeK4_N | CaNA_N | Genotype | Treatment | Behavior | class* |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2 | 309_1 | 0.503643884 | 0.747193224 | 0.4301753 | 2.81632854 | 5.990151664 | 0.218830018 | 0.177565491 | 2.373744337 | 0.232223754 | 1.750935592 | 0.687906244 | 0.306381721 | 0.402698444 | 0.296927319 | 1.022060272 | 0.605672641 | 1.877683671 | 2.308745322 | 0.44159937 | 0.859365767 | 0.416289147 | 0.369608036 | 0.178944258 | 1.866358085 | 3.685247193 | 1.537226709 | 0.264526295 | 0.319676975 | 0.813866457 | 0.165845972 | 0.453909789 | 3.037620642 | 0.369509553 | 0.458538507 | 0.335335828 | 0.825192043 | 0.576915501 | 0.448099271 | 0.58627142 | 0.394721292 | 0.339570613 | 0.482863896 | 0.294169785 | 0.182150472 | 0.84272515 | 0.192608387 | 1.443090669 | 0.29469997 | 0.354604528 | 1.339069956 | 0.170118794 | 0.159102447 | 0.18885166 | 0.106305209 | 0.144989339 | 0.176667682 | 0.125190375 | 0.115290892 | 0.228043456 | 0.14275561 | 0.430957458 | 0.247537821 | 1.603309981 | 2.014874607 | 0.108234339 | 1.044979186 | 0.831556503 | 0.18885166 | 0.122652046 | 0.106305209 | 0.108335872 | 0.427099198 | 0.114783227 | 0.131790029 | 0.128185603 | 1.67565235 | Control | Memantine | C/S | c-CS-m | |
3 | 309_2 | 0.51461708 | 0.689063548 | 0.411770344 | 2.789514042 | 5.685037861 | 0.211636155 | 0.172817023 | 2.292149909 | 0.226972108 | 1.596376881 | 0.69500623 | 0.299051088 | 0.385986773 | 0.281318892 | 0.956675932 | 0.587558708 | 1.725773986 | 2.043036519 | 0.445221892 | 0.834659254 | 0.400364229 | 0.356177514 | 0.17367967 | 1.761046679 | 3.48528707 | 1.509249497 | 0.25572702 | 0.304418672 | 0.780504169 | 0.157193521 | 0.430940286 | 2.921882488 | 0.342279306 | 0.423559858 | 0.324834659 | 0.761717627 | 0.545097287 | 0.420876066 | 0.545097287 | 0.368254577 | 0.321959168 | 0.454519314 | 0.276430557 | 0.182086309 | 0.847614612 | 0.194815275 | 1.439459795 | 0.294059816 | 0.354548277 | 1.306323088 | 0.171427093 | 0.158128945 | 0.184570009 | 0.106592156 | 0.150470868 | 0.178309014 | 0.13427507 | 0.118234503 | 0.238073062 | 0.142036635 | 0.457156163 | 0.257632205 | 1.671737556 | 2.004605195 | 0.109748525 | 1.009883059 | 0.849270413 | 0.200403601 | 0.11668219 | 0.106592156 | 0.10431543 | 0.441581289 | 0.111973507 | 0.13510297 | 0.1311187 | 1.743609645 | Control | Memantine | C/S | c-CS-m | |
4 | 309_3 | 0.509183088 | 0.730246795 | 0.418308781 | 2.687201071 | 5.622058542 | 0.209010905 | 0.175722212 | 2.283336522 | 0.230246795 | 1.561316243 | 0.677348383 | 0.291276067 | 0.381002487 | 0.28171035 | 1.003634972 | 0.602448823 | 1.731872967 | 2.017983547 | 0.467667878 | 0.814329443 | 0.399846949 | 0.36808877 | 0.173904725 | 1.765544289 | 3.571455902 | 1.501243543 | 0.259613545 | 0.3117467 | 0.785154008 | 0.160895351 | 0.423187297 | 2.944136216 | 0.343696193 | 0.425004783 | 0.324851731 | 0.757030802 | 0.543619667 | 0.404629807 | 0.552994069 | 0.363879855 | 0.3130859 | 0.447197245 | 0.256648173 | 0.18438769 | 0.856165847 | 0.200737337 | 1.52436418 | 0.301880744 | 0.386086771 | 1.279600342 | 0.185456294 | 0.148696303 | 0.190532165 | 0.108303056 | 0.145330199 | 0.176212866 | 0.132560376 | 0.117760205 | 0.244817269 | 0.142444967 | 0.510472323 | 0.255343022 | 1.663549904 | 2.016830519 | 0.108196196 | 0.996847617 | 0.846708698 | 0.193684548 | 0.118508228 | 0.108303056 | 0.106219278 | 0.435776875 | 0.111882881 | 0.133361829 | 0.127431075 | 1.926426587 | Control | Memantine | C/S | c-CS-m | |
5 | 309_4 | 0.442106692 | 0.61707615 | 0.358626307 | 2.466947197 | 4.97950319 | 0.222885842 | 0.176462604 | 2.152300801 | 0.207004208 | 1.595086195 | 0.583276775 | 0.296728655 | 0.37708701 | 0.313831953 | 0.875390254 | 0.520293199 | 1.566852179 | 2.132754174 | 0.477670694 | 0.727704629 | 0.385638659 | 0.362970001 | 0.179448894 | 1.286276639 | 2.970137098 | 1.419709515 | 0.259535768 | 0.279218135 | 0.734491652 | 0.162209855 | 0.410614904 | 2.500203611 | 0.344509298 | 0.429211348 | 0.330120809 | 0.746979775 | 0.54676259 | 0.386860323 | 0.547848514 | 0.366770734 | 0.328491923 | 0.442649654 | 0.398534003 | 0.161767701 | 0.760233521 | 0.184169439 | 1.612382051 | 0.29638178 | 0.290679519 | 1.19876451 | 0.159799063 | 0.16611228 | 0.185323468 | 0.103183762 | 0.14065576 | 0.163804222 | 0.123209558 | 0.117439413 | 0.234946711 | 0.145068223 | 0.430995859 | 0.251103116 | 1.484624262 | 1.957233046 | 0.119883239 | 0.990224696 | 0.833276763 | 0.192111873 | 0.13278121 | 0.103183762 | 0.111261965 | 0.391690992 | 0.130405268 | 0.147444165 | 0.146901093 | 1.700563438 | Control | Memantine | C/S | c-CS-m | |
6 | 309_5 | 0.434940244 | 0.617429838 | 0.358802202 | 2.36578488 | 4.718678663 | 0.213105949 | 0.173626964 | 2.134013697 | 0.192157916 | 1.504229891 | 0.550960118 | 0.286961192 | 0.363502081 | 0.277964281 | 0.864912045 | 0.507989795 | 1.480059084 | 2.013696791 | 0.483416141 | 0.687793742 | 0.367530549 | 0.355310863 | 0.174835504 | 1.324694508 | 2.896334094 | 1.35987646 | 0.250704982 | 0.273667249 | 0.702699073 | 0.154827447 | 0.398549752 | 2.456559688 | 0.329125822 | 0.408755203 | 0.313414798 | 0.691956493 | 0.536860481 | 0.360816436 | 0.512823956 | 0.35155096 | 0.312206258 | 0.419094938 | 0.393447026 | 0.16020025 | 0.768112919 | 0.185718259 | 1.645807259 | 0.29682937 | 0.309345015 | 1.206994855 | 0.164650257 | 0.16068697 | 0.188221388 | 0.104783757 | 0.141983034 | 0.167709637 | 0.136837714 | 0.116047838 | 0.255527743 | 0.140870533 | 0.481226533 | 0.25177305 | 1.534835211 | 2.009108608 | 0.119524406 | 0.997774997 | 0.878667779 | 0.205604228 | 0.129954109 | 0.104783757 | 0.110693923 | 0.434153803 | 0.118481435 | 0.140314282 | 0.148379919 | 1.839730218 | Control | Memantine | C/S | c-CS-m | |
7 | 309_6 | 0.447506385 | 0.62817583 | 0.36738809 | 2.38593897 | 4.807635435 | 0.218577766 | 0.176233365 | 2.14128243 | 0.195187525 | 1.442398172 | 0.566339562 | 0.289823901 | 0.363892996 | 0.26683694 | 0.85912085 | 0.521306627 | 1.538244388 | 1.968275306 | 0.495899987 | 0.672402205 | 0.36940449 | 0.357171663 | 0.179728458 | 1.227449926 | 2.956983466 | 1.447909665 | 0.250840167 | 0.284043554 | 0.704395752 | 0.156875924 | 0.391047184 | 2.467132679 | 0.327597795 | 0.404489851 | 0.296276381 | 0.674418605 | 0.539723081 | 0.354214276 | 0.51431644 | 0.347224089 | 0.303132141 | 0.412824304 | 0.382578304 | 0.162330317 | 0.77969457 | 0.186792986 | 1.634615385 | 0.28803733 | 0.332367081 | 1.12344457 | 0.175692873 | 0.150593891 | 0.183823529 | 0.106476244 | 0.13956448 | 0.174844457 | 0.130514706 | 0.115243213 | 0.236849548 | 0.13645362 | 0.478577489 | 0.244485294 | 1.507777149 | 2.003535068 | 0.120687217 | 0.920178167 | 0.843679299 | 0.190469457 | 0.131575226 | 0.106476244 | 0.109445701 | 0.439833145 | 0.11665724 | 0.140766403 | 0.14218043 | 1.816388575 | Control | Memantine | C/S | c-CS-m | |
8 | 309_7 | 0.428032684 | 0.573695789 | 0.342708988 | 2.334223759 | 4.473130107 | 0.225172847 | 0.184003771 | 2.012413576 | 0.195788812 | 1.612036455 | 0.509899434 | 0.299654305 | 0.37115022 | 0.277655563 | 0.844280327 | 0.485386549 | 1.494814582 | 2.01257071 | 0.497485858 | 0.646134507 | 0.395977373 | 0.359522313 | 0.186046512 | 1.10779384 | 2.599622879 | 1.364236329 | 0.261470773 | 0.276241358 | 0.693117536 | 0.162162162 | 0.405562539 | 2.288812068 | 0.345380264 | 0.427561282 | 0.333909491 | 0.757542426 | 0.558610937 | 0.368950346 | 0.544626021 | 0.360307982 | 0.329352608 | 0.420490258 | 0.465116279 | 0.145565999 | 0.70224765 | 0.177033102 | 1.773845525 | 0.292194524 | 0.266857376 | 1.03228443 | 0.147854516 | 0.149816101 | 0.181610135 | 0.097834083 | 0.142787086 | 0.15185942 | 0.115978749 | 0.114752758 | 0.22451982 | 0.144830405 | 0.415529219 | 0.238005721 | 1.338782182 | 1.861708214 | 0.117041275 | 1.028769922 | 0.798283613 | 0.181610135 | 0.141806293 | 0.097834083 | 0.111483449 | 0.406293421 | 0.13722926 | 0.156681651 | 0.157498978 | 1.528483858 | Control | Memantine | C/S | c-CS-m | |
9 | 309_8 | 0.416922604 | 0.564035627 | 0.327702703 | 2.260135135 | 4.268734644 | 0.214834152 | 0.179668305 | 2.007985258 | 0.18980344 | 1.424600737 | 0.501074939 | 0.283015971 | 0.358875921 | 0.256449631 | 0.818642506 | 0.478501229 | 1.409398034 | 1.85703317 | 0.48955774 | 0.628071253 | 0.360718673 | 0.360718673 | 0.171836609 | 1.077395577 | 2.550214988 | 1.316646192 | 0.250614251 | 0.265356265 | 0.676597052 | 0.159551597 | 0.375460688 | 2.281173219 | 0.328163391 | 0.407248157 | 0.322788698 | 0.695178133 | 0.525030713 | 0.340141278 | 0.50982801 | 0.338298526 | 0.298525799 | 0.39296683 | 0.44041769 | 0.147848101 | 0.681940928 | 0.174599156 | 1.795780591 | 0.288523207 | 0.288607595 | 1.152067511 | 0.152405063 | 0.154514768 | 0.182869198 | 0.099493671 | 0.140168776 | 0.158734177 | 0.119578059 | 0.116202532 | 0.246835443 | 0.13443038 | 0.451139241 | 0.241434599 | 1.386075949 | 1.969451477 | 0.116877637 | 0.943544304 | 0.843966245 | 0.191561181 | 0.141012658 | 0.099493671 | 0.113080169 | 0.382531646 | 0.123375527 | 0.155611814 | 0.159409283 | 1.652658228 | Control | Memantine | C/S | c-CS-m | |
10 | 309_9 | 0.386310905 | 0.538428074 | 0.317720418 | 2.125725058 | 4.063950116 | 0.207221578 | 0.167778422 | 1.861513921 | 0.180684455 | 1.261890951 | 0.476653132 | 0.266966357 | 0.337006961 | 0.242604408 | 0.748259861 | 0.458961717 | 1.341792343 | 1.822070766 | 0.464472158 | 0.600638051 | 0.326566125 | 0.328886311 | 0.170388631 | 1.008845708 | 2.434599768 | 1.252030162 | 0.230423434 | 0.252610209 | 0.635585847 | 0.154147332 | 0.351218097 | 2.139211137 | 0.309164733 | 0.378480278 | 0.294518561 | 0.636890951 | 0.484918794 | 0.32337587 | 0.479988399 | 0.312064965 | 0.279292343 | 0.357598608 | 0.421693735 | 0.150120856 | 0.710808011 | 0.167472376 | 1.805248619 | 0.294457873 | 0.294112569 | 1.107907459 | 0.158839779 | 0.148653315 | 0.178522099 | 0.105145028 | 0.137776243 | 0.160393646 | 0.123964088 | 0.116799033 | 0.233857044 | 0.132596685 | 0.455973757 | 0.236015193 | 1.404178177 | 1.958736188 | 0.11386395 | 0.94690953 | 0.83218232 | 0.186377762 | 0.139589088 | 0.105145028 | 0.105490331 | 0.435687155 | 0.125172652 | 0.152710635 | 0.158235497 | 1.834599448 | Control | Memantine | C/S | c-CS-m | |
11 | 309_10 | 0.380827447 | 0.499293643 | 0.362462159 | 2.096266398 | 3.598587286 | 0.22764884 | 0.188092836 | 1.717860747 | 0.188092836 | 1.414328961 | 0.455499495 | 0.324117053 | 0.368314834 | 0.283753784 | 0.743491423 | 0.44419778 | 1.355398587 | 1.783249243 | 0.493037336 | 0.570534813 | 0.335418769 | 0.392129162 | 0.198385469 | 0.906155399 | 2.169929364 | 1.248234107 | 0.257719475 | 0.301513623 | 0.636730575 | 0.174369324 | 0.380423814 | 1.922906155 | 0.373965691 | 0.433501514 | 0.394349142 | 0.742078708 | 0.553178607 | 0.357214934 | 0.530978809 | 0.358627649 | 0.336024218 | 0.426034309 | 0.505751766 | 0.14006295 | 0.637927158 | 0.175584532 | 1.926596223 | 0.301821043 | 0.24977518 | 0.930980216 | 0.145458633 | 0.166254496 | 0.171088129 | 0.09330036 | 0.12443795 | 0.150629496 | 0.117580935 | 0.126573741 | 0.224145683 | 0.148156475 | 0.410971223 | 0.244829137 | 1.288669065 | 1.818907374 | 0.13995054 | 0.970323741 | 0.803394784 | 0.189523381 | 0.183678058 | 0.09330036 | 0.116906475 | 0.414793165 | 0.146133094 | 0.188848921 | 0.192333633 | 1.516861511 | Control | Memantine | C/S | c-CS-m | |
12 | 309_11 | 0.366511251 | 0.513277924 | 0.327792418 | 2.072572471 | 3.66105818 | 0.229474965 | 0.193796878 | 1.724508413 | 0.185282789 | 1.31867018 | 0.461179809 | 0.290289884 | 0.3794851 | 0.271234543 | 0.765659842 | 0.449422258 | 1.297993108 | 1.756132171 | 0.509831745 | 0.547536996 | 0.346036894 | 0.362659639 | 0.196229475 | 0.891952159 | 2.171903507 | 1.231096696 | 0.266166633 | 0.262720454 | 0.635313197 | 0.169673627 | 0.418812082 | 1.957834989 | 0.34684776 | 0.428137036 | 0.352118386 | 0.693087371 | 0.54672613 | 0.343807014 | 0.524021893 | 0.341374417 | 0.323535374 | 0.406649098 | 0.513277924 | 0.144505369 | 0.662097327 | 0.173292209 | 1.902901531 | 0.298377884 | 0.275416952 | 0.899017592 | 0.144391135 | 0.169979438 | 0.183801691 | 0.094356865 | 0.128169979 | 0.149988577 | 0.125999543 | 0.119716701 | 0.235549463 | 0.134110121 | 0.429403701 | 0.250628284 | 1.326707791 | 1.861549006 | 0.126799178 | 0.940370117 | 0.842472013 | 0.190769934 | 0.168037469 | 0.094356865 | 0.131254284 | 0.385423806 | 0.151816313 | 0.184601325 | 0.193054604 | 1.613548092 | Control | Memantine | C/S | c-CS-m | |
13 | 309_12 | 0.364153907 | 0.499411072 | 0.355123675 | 2.006870828 | 3.466627405 | 0.216332941 | 0.204358068 | 1.672555948 | 0.190223793 | 1.166077739 | 0.447192776 | 0.27718885 | 0.361405575 | 0.26442874 | 0.743031017 | 0.443855516 | 1.250098155 | 1.690812721 | 0.492343934 | 0.549862583 | 0.323125245 | 0.344719278 | 0.197879859 | 0.862583431 | 2.108755399 | 1.20691009 | 0.243423636 | 0.281311347 | 0.615822536 | 0.160581076 | 0.368080094 | 1.887711033 | 0.333922261 | 0.408912446 | 0.33451119 | 0.666274048 | 0.529053789 | 0.326266196 | 0.505300353 | 0.330977621 | 0.319199058 | 0.384766392 | 0.501570475 | 0.142299503 | 0.675065058 | 0.180151408 | 2.001656021 | 0.306837 | 0.287319612 | 0.967707594 | 0.159451147 | 0.15554767 | 0.17411876 | 0.098414952 | 0.135557133 | 0.160752307 | 0.127986752 | 0.115448308 | 0.236337828 | 0.141116631 | 0.455050863 | 0.249704282 | 1.30305181 | 1.913532056 | 0.124201561 | 0.911521173 | 0.836172226 | 0.194819021 | 0.166311805 | 0.098414952 | 0.125266146 | 0.442394133 | 0.149988171 | 0.191861841 | 0.195528744 | 1.722971374 | Control | Memantine | C/S | c-CS-m | |
14 | 309_13 | 0.364873351 | 0.482101737 | 0.312539251 | 1.946200544 | 3.349591794 | 0.230898053 | 0.188821436 | 1.508687461 | 0.171027842 | 1.353359849 | 0.471844254 | 0.272137325 | 0.340590329 | 0.256018422 | 0.723047938 | 0.417416789 | 1.226711325 | 1.737701486 | 0.461168097 | 0.494871258 | 0.384969646 | 0.339543647 | 0.199288256 | 0.869583421 | 1.925685577 | 1.149047519 | 0.273812016 | 0.256018422 | 0.612727653 | 0.16474775 | 0.366338706 | 1.749214988 | 0.322378062 | 0.426418254 | 0.37366548 | 0.690391459 | 0.528155746 | 0.353150513 | 0.520619636 | 0.32593678 | 0.332426209 | 0.466610844 | 0.464098807 | 0.12679558 | 0.589502762 | 0.167403315 | 1.904005525 | 0.279696133 | 0.244889503 | 0.944060773 | 0.137845304 | 0.176381215 | 0.175276243 | 0.097651934 | 0.123756906 | 0.15 | 0.117403315 | 0.126657459 | 0.223480663 | 0.14198895 | 0.395441989 | 0.277624309 | 1.251933702 | 1.760635359 | 0.160773481 | 0.997237569 | 0.80980663 | 0.203314917 | 0.200276243 | 0.097651934 | 0.126933702 | 0.440331492 | 0.168370166 | 0.236878453 | 0.214088398 | 1.426933702 | Control | Memantine | C/S | c-CS-m | |
15 | 309_14 | 0.381910612 | 0.485914001 | 0.31095107 | 1.958907011 | 3.349290405 | 0.225799619 | 0.188519381 | 1.50900233 | 0.179834781 | 1.219656852 | 0.463249312 | 0.284261809 | 0.36030502 | 0.262868036 | 0.755348443 | 0.41897903 | 1.197203982 | 1.686083457 | 0.485066723 | 0.524465156 | 0.343359458 | 0.347172209 | 0.214573184 | 0.814022453 | 1.956576996 | 1.137894514 | 0.239779708 | 0.25672527 | 0.579114594 | 0.164371955 | 0.367295065 | 1.770599449 | 0.339970345 | 0.427028172 | 0.370684177 | 0.68904893 | 0.524041517 | 0.337216691 | 0.4956577 | 0.329379369 | 0.321965685 | 0.403728024 | 0.462825673 | 0.134298973 | 0.611165799 | 0.170862045 | 1.972577697 | 0.283785684 | 0.254957109 | 0.929545774 | 0.136408381 | 0.172971453 | 0.174377725 | 0.094642104 | 0.142314724 | 0.154408663 | 0.117283083 | 0.123892561 | 0.24483195 | 0.136127127 | 0.415412741 | 0.252003938 | 1.288707636 | 1.792434257 | 0.131345802 | 0.980874701 | 0.832794262 | 0.190127971 | 0.196034313 | 0.094642104 | 0.125017578 | 0.422162846 | 0.178737168 | 0.215581493 | 0.22528477 | 1.500070314 | Control | Memantine | C/S | c-CS-m |